As part of the INTOXICOM Implementation Study for the ELIXIR Toxicology Community a series of workshops is organized (Martens et al., 2024). Here, we here report on the 3rd workshop, titled “Making toxicology tools more accessible and interoperable” which was held from 26 to 27 March 2025 at the SciLifeLab at Uppsala University in Sweden. The workshop welcomed 29 participants from Sweden, The Netherlands, Cyprus, Switzerland, Italy, Greece, France, and Norway. This 3rd INTOXICOM workshop covered various aspects of making computational tools available and how they are used. Several projects, such as NanoSolveIT (Afantitis et al., 2020), ONTOX (Vinken et al., 2021), and VHP4Safety (Kienhuis et al., 2024), already make computational toxicology services available, but the field of integrating computional toxicology dates back much longer, such as Bioclipse developed at Uppsala University (Willighagen et al., 2011), making it a perfect location to have held this workshop.